The entourage effect, the synergy that does us good

Le hemp is renowned for its exceptional virtues, its ancestral use, its fibres and seeds, as well as its therapeutic benefits. It is rich in more than 500 chemical compounds such as cannabinoids, terpenes and flavonoids, which together contribute to what is known as theentourage effect. We'll be taking a closer look at the entourage effect, analysing the compounds in hemp, how they interact and their health benefits. You will also discover how to select hemp-based products that maximise this effect, depending on your personal objectives.

What is the entourage effect?

The entourage effect is a synergy where the components of hemp reinforce each other to potentiate their effects. Visit CBD (cannabidiol) and THC (tetrahydrocannabinol) are the best known, but they coexist with more than a hundred others. cannabinoids with different influences. What's more, the terpeneswhich characterise the smell and taste of hempalso affect the effects of cannabinoids and have their own effects. assets.

The different compounds in hemp

Hemp is an exceptionally rich plant in chemical compoundswidely recognised for their virtues therapeutics. These compounds fall into three main categories: the cannabinoidsthe terpenes and flavonoids. Each group has different properties unique and makes a significant contribution to the so-called entourage effect ".

Cannabinoids

Cannabinoids are substances that interact with the nervous system. endocannabinoid of the body. This system, which is spread throughout the body, plays a key role in the control functions physiological such as pain, inflammation, mood and appetite, sleep and memory. Hemp contains over 100 different cannabinoids, including CBD (cannabidiol) and the THC (tetrahydrocannabinol) are the best known.

• Le CBG or cannabigerol, is the 'first' cannabinoid to develop in cannabis, from which the other cannabinoids are derived. It is thought to have soothing properties and antioxidants.
• Le CBD is recognised for its potential properties anti-inflammatories, antioxidants and neuroprotective. It is non-psychotropicIt does not alter perception or behaviour. It may also reduce the less desirable effects of THC, such as anxiety or paranoia.

• Le CBNis also known as cannabinol. It is thought to combat inflammation and stimulate the appetite. It is also known to help reduce anxiety and helps to find the sleep by providing a relaxing effect that helps you fall asleep.

• As for the THCIt is best known for the psychotropic effects associated with cannabis consumption. In addition to its euphoriant and relaxing, it is said to have analgesic properties and antiemetics (acts on nausea and vomiting). However, it should be used with caution, as it can cause side-effects such as drowsiness. In BelgiumTHC is authorised in products containing hemp provided it does not exceed the legal threshold of 0.3 %.

Find out more about Belgian law on CBD and cannabinoids in our article Legislation on CBD in Belgium.

Terpenes

Terpenes are the compounds responsible for thesmell and flavour characteristics of hemp. These aromatic substances don't just arouse our senses; they also play a role in the properties of the plant. antibacterialThe plant's medicinal, antifungal and anti-inflammatory properties. The most commonly found in hemp include myrcenethe limonenethe pinene and the linalool. Terpenes can also influence the activity of cannabinoids by modulating their absorption into the body.

Flavonoids

The flavonoids are the plant pigments that give hemp its distinctive colours and aromas. They defend the plant against aggressions such as UV rays, parasites and diseases. In addition to their protective role, these compounds have the following properties antioxidants and anti-inflammatories. The interactions of flavonoids with cannabinoids and terpenes can amplify or vary their effects on the body, thus enriching their overall impact on health.

The mechanisms of the entourage effect

Let's find out how hemp s, such as cannabinoids, terpenes and flavonoids, combine to induce theentourage effect. How do these elements interact to modulate and enhance the effects of hemp on the body?

The endocannabinoid system

Le endocannabinoid system regulates numerous physiological functions, including pain, inflammation, mood, appetite, sleep and memory. It is made up of cannabinoid receptors (CB1 and CB2), endocannabinoids and enzymes that manage the synthesis and breakdown of these molecules. CB1 receptors are found mainly in the brain and nervous system, while CB2 receptors are found in the immune system and peripheral organs.

Cannabinoids in hemp, such as THC and CBD, bind to these receptors and influence their activity. The THC activates the receptors CB1 and CB2 to produce psychotropic effects and therapeutics. Le CBDwhich has a greater affinity for the CB2 than for the receiver CB1acts as an antagonist, regulating the effects of THC by reducing side effects such as anxiety or to reinforce therapeutic effects such as analgesia or anti-inflammatory properties.

Interaction with terpenes and flavonoids

The terpenes and flavonoids also play a key role. These compounds can exert their own effects and also modulate those of cannabinoids.

• For example, the terpene myrcene can increase the permeability of the blood-brain barrier, making it easier for THC to enter the brain.
• Le pinene may prevent the breakdown of acetylcholine, a neurotransmitter linked to memory, and potentially lessen the impact of THC on memory.
• The flavonoidsare often beneficial in the following ways antioxidantsThey are also anti-inflammatory and anti-allergic, and can modify the effects of cannabinoids by attaching to receptors or changing their bioavailability.¹.

The benefits of the entourage effect

Le hemp is rich in compounds which, when combined, give rise to what is known as the entourage effect. But how does this synergy benefit our health and well-being? Let's take a closer look at how the entourage effect can boost the effectiveness of hemp-derived products.

An amplified therapeutic effect

One of the major advantages of the environment lies in its ability to produce a stronger therapeutic response while reducing the amount of product required. The various compounds in hemp work together to target different systems biologicalThis broadens their field of action and their bioavailability. Take CBD and the THCwhich, when combined, offer more significant relief from paininflammation, anxiety and nausea. The terpenes and flavonoids also play a role in modulating the absorption and metabolism of cannabinoids to maximise their impact.

Minimisation of side effects

Another advantage of the entourage effect is its capacity to minimize the undesirable side effects associated with certain components of hemp. In particular THCThis drug, famous for its psychotropic effects, can cause tachycardia and dry mouth, drowsinessor even paranoia. Thanks to the entourage effect, it is possible to reduce the dose of THC needed to benefit from its virtues. therapeuticsthus mitigating the risk of psychotropic drugs. CBD and certain terpenes can moderate the influence of THC on the brain by influencing the way it interacts with the receivers cannabinoids.

How to choose your hemp-based products

Choosing quality hemp

The quality of hemp is paramount. To guarantee the security and efficiency of your product, give priority to products from organic hempgrown without the use of pesticides or other harmful chemicals. Opt for products made in Belgium or Europe, to ensure that they respect the environment. health standards strict. Find out more about the origintraceability and certifications by consulting the manufacturers' websites or checking the analyses of laboratory.

The spectrum of CBD oil

There are three types of spectra: complete, large and isolate. Your choice will depend on your needs and your personal preferences linked to the presence of THC.

• Oils for full spectrum contain all the components of the hemp (terpenes, flovonoids and cannabinoids), including THC. This maximises the effect entourage.
• Those at broad spectrum contains no trace of THC. It is popular with athletes and people who have to undergo screening on a regular basis.
• L' CBD isolate focus on a single component: CBD.

How should CBD oil be used?

The method of consumption is another aspect to consider, as it impacts on the effectiveness, speed and persistence of the effect. Options includeingestion, l'inhalationthe vaporisation and thecutaneous application. Each method has its own benefits and limitations.

• L'ingestion offers a slow, long-lasting release, but with variable bioavailability. Belgian law does not allow us to market our CBD oils as ingestible products. We advise you to read our article on CBD legislation in Belgium in 2024.
• L'inhalation provides an immediate effect, while vaporisation offers optimised absorption but requires special equipment.
• L'cutaneous application is ideal for a located.

Conclusion

We hope this article has shed some light on the surrounding effect of hempThis fascinating concept stems from the beneficial interaction between the cannabinoids, terpenes and flavonoids present in the plant. Understanding this effect means you can make the most of hemp's potential benefits for your health. health and well-being, whether through increased efficiency therapeuticWe're here to help you make the most of your treatment, reduce side-effects and tailor products to your specific needs.

You are now in a better position to make informed choices about the hemp-based products best suited to your personal situation, taking into account criteria such as qualitythe cannabis spectrum and the method of administration.

Explore our range of CBD oils and enjoy all the benefits of hemp right now!

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¹ Bioavailability refers to the speed and extent to which the active ingredient passes into the general circulation, reaching the site of action.